News
GreenScreen and BlueScreen to be discussed in IWGT Plenary Session
Posted on May 10, 2013 by Andrew Eaton
The 4-yearly International Workshops on Genotoxicity Testing (IWGT) will again be held as a satellite to the International Conference on Environmental Mutagens (ICEM) which is being held in Brazil 3-8 November 2013. This year, GreenScreen HC and BlueScreen HC will be discussed as part of the Plenary session on “The shape of genotoxicity testing in the future”. For more information about ICEM, or to register for the conference, visit here For information on the IWGT satellite meeting, visit here
New Paper Sheds Light on Role of WT1 Protein in p53-Dependent and p53-Independent Pathways for GADD45a Regulation
Posted on May 10, 2013 by Andrew Eaton
A new paper by Gentronix researchers, published in the journal Mutagenesis, increases our understanding of why the GADD45a gene has a more specific response to genotoxic damage than other p53 regulated genes. GADD45a gene expression, which is exploited in the GreenScreen HC and BlueScreen HC genotoxicity assays, plays an important role in mediating the adaptive response to genotoxic stress through participation in cell cycle checkpoints and DNA repair processes. Understanding how the gene is regulated is therefore important because interference could result in misleading hazard prediction. Whist GADD45a is regulated in part by the tumour suppressor protein p53 (the “guardian…
Follow Gentronix on Twitter
Posted on April 19, 2013 by Andrew Eaton
Gentronix is now tweeting headlines of all of the latest news on Twitter. Follow us for up to date information on early genetic toxicology screening www.twitter.com/GentronixLtd
Epigenetics presentation at ’ADME and Predictive Toxicology’ meeting
Posted on March 21, 2013 by Andrew Eaton
Gentronix founder and CSO, Prof. Richard Walmsley will be giving an oral presentation at the ’ADME and Predictive Toxicology’ meeting in Barcelona on the 12th April 2013. The talk, entitled, “The Accurate Detection of Genotoxic Carcinogens, and the New Challenges Presented by ‘Epi-genotoxicity’” will be presented in the session entitled “Genotoxicity and Toxicokinetic Modelling”. Further details can be found at the conference website Professor Walmsley can be contacted through the Contact us page